Contact Us

We are available via the following contact details:

Contact	Details
Email
Phone	+44 (0) 207 600 3193
Fax	+44 (0) 207 606 0506
Address	Logical Medical Systems Ltd, 29-30 Newbury Street, London EC1A 7HU, United Kingdom

Logical Medical Systems is registered in England and Wales with company number 02102797

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Please fill in the form below or contact us above to ask a question regarding any aspect of αlpha. We also offer limited customisation to match you screening program or laboratory information system.

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Our history

αlpha was originally developed by Professors Wald and Cuckle and launched in 1988 for Down's syndrome and neural tube defect screening. Professor Sir Nicholas Wald has continued to direct its development.

This Citation Classic describes the Triple test which was the start of multiple marker screening for Down's syndrome and led to the production of αlpha which pioneered the use of interpretive software in this way.

Since then αlpha has been developed to include many medical advances in the field including screening for pre-eclampsia and the identification of pregancies at high risk of trisomy 18, SLOS and trisomy 13.

Professor Wald is known for his research in epidemiology and preventive medicine. He has pioneered the field of antenatal screening for congenital malformation and made discoveries that form the basis of screening for neural tube defects and Down’s syndrome in early pregnancy. He showed, in a large randomised trial, that a lack of folic acid is a cause of neural tube defects, and that an adequate intake of the vitamin immediately before pregnancy can prevent most cases. He has demonstrated that passive smoking is a cause of lung cancer and with Professor Law showed it also increased the risk of ischaemic heart disease. Screening procedures for early detection of certain cancers, notably breast cancer, have been advanced from his work. With Professor Law, he clarified the relationship between salt intake, blood pressure and cardiovascular disease.